Thinking About Trimix?
What You Need To Know
Thinking About Trimix Injections?
Talk to a doctor at Boston Medical Group about your options for treating your erectile dysfunction before choosing if Trimix is right for you. Our doctors are able to pinpoint the root of your erectile dysfunction with precision thanks to our professional expert team.
Why not consult the professionals at Boston Medical Group, who have been treating erectile dysfunction in men for two decades, before you decide to use Trimix? You may just be a phone call away from experiencing complete sexual rejuvenation once again.
- Table Of Contents
- What Is Trimix
- Pills VS. Trimix Injections
- Trimix Frequently Asked Questions
What Is Trimix
TriMix is a medicine that is, in truth, three drugs mixed into one, hence the name TriMix. It is made in a sterile lab in compounding pharmacies, which is why it’s a compound drug (compounded medication). This means that it can only be filled at pharmacies that make medications in this manner. It's also made just for you and your needs, which means your doctor or nurse may suggest a certain pharmacy they know and trust to make your medicine.
The FDA hasn't given TriMix the green light, although it has three components. Some doctors give it to men with erectile dysfunction (ED) or penile rehab, especially after prostate surgery. This is meant to help you get an erection again after your procedure.
TriMix usually has a mix of alprostadil, phentolamine, and papaverine as its active ingredients. So, it's called "TriMix," where "tri" means "three." In the same way, QuadMix has four ingredients, and BiMix has only two.
In fact, alprostadil is a common ingredient in many other ED drugs that the FDA has approved. Among these are Edex, Caverject, and Caverject Impulse, but alprostadil is the only active drug in these medicines.

How Trimix Helps With ED
Your doctor might want you to test the drug in their office first before starting TriMix. Based on your reaction, they can use this information to determine the appropriate initial dose. They might also teach you how to administer the injection on your own during this period.
TriMix is normally provided in a vial with syringes so that you can administer the injections on your own. Keeping your prescription in the freezer will typically extend its shelf life. So, before using it, you might need to defrost it. When it's ready, remove your dose from the vial and double-check the dosage.
Your dose will be injected into a specific location on your penis. To prevent the formation of scar tissue, rotate the injection locations each time. It should not be injected into blood vessels since this may result in bruising. Apply pressure to the injection site for two to three minutes after extracting the needle. This may aid in reducing bruising or bleeding.
In most cases, TriMix is successful in treating erectile dysfunction in men. It is effective in 90% of the cases. An erection that is strong and long-lasting is the typical outcome of receiving a Trimix injection.
Does Trimix Have Side Effects?
Despite the fact that TriMix is mostly a safe drug to administer, some men may encounter a few negative effects. Several potential adverse effects include
- If adequate procedures are not used when providing the injection, pain may develop at the injection site. To lessen the possibility of pain, apply topical anesthetic treatments.
- It's possible to experience priapism, a prolonged erection. This is a medical emergency and needs immediate medical attention.
- If a vein is accidentally ruptured when providing the TriMix injection, bleeding may happen at the injection site.
- If adequate injection technique is not followed, temporary swelling of the penile skin may develop.
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Pills VS. Trimix Injections
Over 70% of men with erectile dysfunction benefit from Viagra, which is also simple to use. TriMix works for a wider range of patients, including those who cannot take Viagra. TriMix works for >95% of men while Viagra only works for 70% of men with moderate to severe ED, despite the fact that TriMix is generally used by men for whom Viagra and prostaglandin do not function well when compared "Apples to Apples."
TriMix is more effective than Viagra, but because Viagra is easier to use, more men choose to use it. TriMix is typically only prescribed to those for whom oral drugs like Viagra and Cialis do not work because they are simpler to use and do not require injections.
Frequently Asked Questions (FAQ) About Trimix
What is TriMix?
Trimix is an injectable medication used to treat erectile dysfunction (ED). It is a combination of three drugs that work by enhancing blood flow to the penile tissue, helping men achieve and maintain an erection.
How does Trimix work for erectile dysfunction?
Trimix increases blood flow by relaxing the smooth muscle in the penile arteries and blood vessel walls, allowing more blood to enter the erectile tissues. Unlike oral ED medications, Trimix is injected directly into the penis for faster and more reliable results.
How is Trimix different from oral ED medications?
Oral medications (like Viagra or Cialis) rely on systemic absorption and may not work for all men. Trimix injections bypass digestion, providing a stronger, more predictable response by targeting penile blood flow directly.

How effective is Trimix?
Trimix is highly effective, with many men achieving a full erection suitable for sexual activity. Your provider may use an erection scale to adjust your personalized treatment plan.
Is TriMix covered by insurance?
Patients who order TriMix for usage in their homes are normally responsible for covering the whole cost of the medication themselves. Depending on the needs of the patient, the cost of a single dose of TriMix can range anywhere from a few dollars (between $2 and $3) to thirty dollars (at least $30).
What is in TriMix?
Alprostadil, phentolamine, and papaverine are all regarded to be vasodilators, and these are the three components that make up TriMix. They accomplish this by dilating blood vessels, which in turn increases the amount of blood that flows to the penis. This can lead to the development of an erection.
What should I do if I have a prolonged erection?
An erection that lasts more than 4 hours is a medical emergency. Go to the emergency room immediately to prevent damage to penile tissue.
How should I store Trimix?
- Keep the medication vial refrigerated.
- Avoid expired medication—discard if outdated.
- Store in a sterile environment to prevent contamination.
Can I use Trimix with other ED treatments?
Consult your healthcare provider before combining Trimix with other ED treatments (like oral medications or pseudoephedrine HCl) to avoid complica
What precautions should I take?
- Avoid air bubbles in the syringe.
- Rotate injection sites to prevent scar tissue.
- Follow proper injection technique to minimize risks.
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Are there serious side-effects to TriMix?
Mild to severe TriMix injection side effects are less frequent. However, they do happen occasionally. Nonetheless, we want to emphasize to patients that they are all different. As a result, it's crucial to keep an eye out for adverse effects during your first few uses of TriMix and to inform your healthcare professional if any do arise. The less frequent side effects include:
- Vomiting, nausea, stomach pain, or diarrhea.
- An allergic response (hives, swelling, itching, etc.)
- Abruptly lowering blood pressure.
- Higher heart rate.
- Irregular heartbeat.
- Scarring or fibrosis near the injection site.
Most of the time, the worst side effects of TriMix injection come from using too much or more often than the instructions say. This can cause an erection that lasts for 4 hours or more and doesn't go away by itself.
Boston Medical Group and the specialists affiliated with it offer treatments for a variety of conditions affecting men's health. The medical professionals at BMG are on the lookout for these issue areas and the possible influences those areas may have on the patient's health. Call us today or make an online appointment so we can enhance your sexual lifestyle!